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RUI: Chromosome organization in cellular development

PI: Lisa Hua
Department: Biology
School or Division: School of Science & Technology
Sponsor: National Science Foundation
Calendar Start & End Date: -
Funding Amount: $600,000

The goal of this project is to uncover how human cells regulate their chromosome organization during cell division throughout normal, and disease states. Chromosomes are packaged DNA structures that consist of an individual’s genetic information. During cell division, chromosomes will duplicate, and divide equally among two daughter cells. Abnormalities that occur during cell division in humans can lead to detrimental consequences, and disease. This project supports a research group in a Hispanic serving institution dedicated to understanding the fundamental principles of chromosome organization. It also provides a strong foundation for recruitment, and accessibility of under-represented student populations in the life sciences. Life science research engagement, and participation will also be made available through the local community across multiple populations, in particular community college, and high school students, and adult seniors to promote outreach diversity, and equity.