Haloperoxidase Mimetics

Presenter: Brandon Johnson

Co-Presenter(s):
Will Dagnino

Presenter Status: Undergraduate student

Department: Chemistry

Screenshot URL: https://drive.google.com/uc?id=1oi9CdaHTkB9qpJA6n_gQr-OxeYgCFiPs

Abstract:
The synthesis of both salen and salicylaldehyde-aminomethyl benzimidazole are key precursors to the synthesis of vanadate-dependent haloperoxidases. The synthesis of a vanadate-dependent haloperoxidase is important due to the nature of the complex being able to research and examine the active site. The active site is of interest due to the ability to oxidize halides and sulfides when peroxide is present. The two ligands that were synthesized would have allowed us to compare a known vanadium complex that correctly displayed the desired active site and compare that to a different vanadium complex that we would synthesize and compare to the known complex. The known complex would have used a ligand called salicylaldehyde-aminomethyl benzimidazole to create a vanadium complex and compare that to a complex that uses salen as the ligand.