Haloperoxidase Mimetic

Model VHPO catalyst

Presenter: Lauren Curlee

Co-Presenter(s):
Tessa Lane

Presenter Status: Undergraduate student

Academic Year: 20-21

Semester: Spring

Faculty Mentor: Jon Fukuto

Department: Chemistry

Funding Source/Sponsor: Class Project

Screenshot URL: https://drive.google.com/uc?id=1UQ96bx8incuxxVGHAm2sGUs1QefPsMFm

Abstract:
Haloperoxidases are a group of enzymes, known as peroxidases, capable of mediating the oxidation of halides by hydrogen peroxide. Vanadium dependent haloperoxidases (VHPOs) catalyze the 2-electron oxidation of halides by peroxide though a Lewis acid type mechanism. Vanadium is the second most abundant transition metal in the ocean and VHPOs can be found in marine life which aid in the oxidation of halides to hypohalous acid. The production of hypohalous acid benefits marine life by protecting from parasite and fungi infestation. (Rehder, 2014)